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Histomorphometric Differences in Tibial Cortical Bone Based on Sampling Location

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dc.contributor.advisor Grine, Frederick E. en_US
dc.contributor.author Blatch, Stepahnie Nicole en_US
dc.contributor.other Department of Anthropology en_US
dc.date.accessioned 2013-05-24T16:38:12Z
dc.date.accessioned 2015-04-24T14:45:36Z
dc.date.available 2013-05-24T16:38:12Z
dc.date.available 2015-04-24T14:45:36Z
dc.date.issued 2012-08-01 en_US
dc.identifier.uri http://hdl.handle.net/1951/60208 en_US
dc.identifier.uri http://hdl.handle.net/11401/71022 en_US
dc.description 87 pg. en_US
dc.description.abstract Histomorphometric analysis of cortical bone is often used to estimate age at death of skeletons or to make inferences about mobility in past populations. Although previous studies have indicated that remodeling is variable within a single cross-section of bone, there has been little examination of the nature of these differences in the human tibia. This study investigated whether there are differences in remodeling based on sampling location in human tibiae, specifically examining inter-quadrant differences (anterior, posterior, medial, and lateral) as well as differences between periosteal, endosteal, and midcortical sampling locations. Slides of undecalcified sections of human tibiae at midshaft (N=10) were used to analyze histomorphometric properties including percent remodeled bone, osteon population density (OPD), Haversian canal size, and osteon size. Results indicate that there is a difference in remodeling of the cortical bone that is dependent on sampling location. Remodeling parameters differ between anatomical quadrants, with the anterior quadrant typically exhibiting higher rates of remodeling. Midcortical sampling locations exhibited greater remodeling than either endosteal or periosteal regions. Furthermore, the selection of magnification level and field size can significantly affect the measurement of OPD. These results support the idea that remodeling can progress in contrasting ways between various areas of the same cross- section of bone. Therefore, care should be taken when comparing histomorphometric properties from different areas of tibial cortical bone. en_US
dc.description.sponsorship This work is sponsored by the Stony Brook University Graduate School in compliance with the requirements for completion of degree. en_US
dc.format Monograph en_US
dc.format.medium Electronic Resource en_US
dc.language.iso en_US en_US
dc.publisher The Graduate School, Stony Brook University: Stony Brook, NY. en_US
dc.subject.lcsh Physical anthropology en_US
dc.subject.other histomorphometrics, osteon, remodeling, tibia en_US
dc.title Histomorphometric Differences in Tibial Cortical Bone Based on Sampling Location en_US
dc.type Thesis en_US
dc.mimetype Application/PDF en_US
dc.contributor.committeemember Baab, Karen L. en_US
dc.contributor.committeemember Jungers, William L. en_US


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